IMMUNE PARAMETERS OF THE PERITONEAL FLUID IN UTERINE MYOMA. PROGNOSTIC RELEVANCE

Abstract

Abstract. The study of immune parameters of 25 healthy fertile women, 63 women with uterine myoma of small stable size and 84 women with rapidly growing myoma was performed. The peritoneal fluid was taken as the material for investigation. It was found that rapid growth of myoma was accompanied by impairment of functional activity of immunocompetent cells of peritoneal fluid such as interruption of regulatory lymphocytes activity and functional activity of macrophages, increase in the amount of immature lymphocytes and activation of cytokine cascade with elevation of growth factors production.

Keywords

• immunity
• peritoneal fluid
• uterine myoma
• il–2