Molecules (Nov 2013)

A Bicyclic Diterpenoid with a New 15,16-Dinorlabdane Carbon Skeleton from Leonurus japonicus and Its Coagulant Bioactivity

  • Xiao-Mei Zhao,
  • Liang Xiong,
  • Fu Peng

DOI
https://doi.org/10.3390/molecules181113904
Journal volume & issue
Vol. 18, no. 11
pp. 13904 – 13909

Abstract

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A new 15,16-dinorlabdane diterpenoid 1 and a known labdane diterpenoid 2, together with three known ergosterols 3–5, were isolated from the EtOAc-soluble portion of the EtOH extract of Leonurus japonicus. Their structures were elucidated by physical and spectroscopic analysis. Compound 1 showed in vitro coagulant activity in the APTT, PT, TT, and FIB assays.

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