Genetically Determined TNF-α Secretion Influences the Development of Dermatomyositis and Systemic Lupus Erythematosus

Affiliations

Dourmishev Lyubomir A.: Department of Dermatology and Venereology, Medical University of Sofia, Sofia, Bulgaria
Hristova Maria H.: Department of Nephrology, Faculty of Medicine, Medical University of Sofia, Sofia, Bulgaria
Kamenarska Zornitsa G.: Molecular Medicine Center, Medical University of Sofia, Sofia, Bulgaria
Savov Alexey S.: National Genetic Laboratory, Maichin Dom Hospital, Bulgaria
Vinkov Anton I.: Department of Neurology, Hôpitaux Drôme Nord, Romans-sur-Isère, France
Kaneva Radka: Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University of Sofia, Sofia, Bulgaria
Mitev Vanjo: Department of Medical Chemistry and Biochemistry, Molecular Medicine Center, Medical University of Sofia, Sofia, Bulgaria

Abstract

Background: Abnormal secretion of TNF-α is known to play a role in the pathogenesis of dermatomyositis and systemic lupus erythematosus.