Фармацевтичний журнал (May 2020)
Comparative analysis of nootropic means of consumption in Ukraine, Estonia and Norway
Abstract
Cerebrovascular disease develops in neurodegenerative, vascular or cerebrovascular diseases of the brain. For their treatment, nootropic agents have neurotrophic, neuroprotective effects, increase brain energy exchange and cerebral circulation. The purpose of the study was to study the range and consumption of nootropic agents in the pharmaceutical market of Ukraine and to compare the volume and structure of their consumption with Estonia and Norway. The objects of this study were the representatives of two pharmacotherapeutic groups - NO6B «Psychostimulants and Nootropic Drugs» and N06D «Drugs used for dementia» present on the Ukrainian pharmaceutical market. The range of these drugs and the average retail price of their packs in the pharmacy network of Ukraine during the studied period were determined using the Morion Company Pharmexplorer market research system (as of December 2014, 2015, 2016, 2017). Drugs were performed according to DDDs/1 000 inhabitants/day or DID, using pharmacoepidemiological method of study ‒ ATC/DDD methodology. In the pharmaceutical market of Ukraine for 2014‒2017, nootropic drugs were represented from 204 tonnes (in 2014) to 237 tonnes (in 2017), based on 18 MNN, mainly domestic production. Drug prices varied over a wide range, which made it possible to choose a drug with nootropic action, taking into account the patient's financial capabilities. Vinpocetine (0.83‒0.98 DID) and piracetam (0.50‒0.52 DID) were predominantly consumed in the N06B group in Ukraine, while Ginkgo leaves (0.51‒0.59 DID) were the most consumed in the N06D group. and memantine (0.08‒0.18 DID). Consumption leaders are represented in the pharmaceutical market in a significant amount of TH and have a wide range of pricing for drug packaging. Compared to European countries, the consumption of nootropic drugs in Ukraine is almost 3.5 times lower than in Estonia and 2.4 times lower than in Norway. In terms of consumption in Ukraine and Estonia, the leaders were Ginkgo leaves, and in Norway, Donezepil. In the Ukrainian pharmaceutical market there is a sufficient assortment of products with nootropic action of mainly domestic production, which have a wide range of prices for the packaging of drugs. Consumption rates for drugs in Ukraine were low and inferior to two European countries, and in terms of consumption patterns similar to those of nootropic drugs in Estonia.
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