Pediatric Hematology Oncology Journal (Dec 2024)
Mucor thriving on iron in beta thalassemia major: A case of rhino-orbital mucormycosis
- Dhaarani Jayaraman,
- Harshavardhan Mahalingam,
- Naga Geetha Rani Mangam,
- Swati Narasimhan,
- Padmasani Venkat Ramanan,
- K. Stephen Sudhakar,
- Prasanna Kumar S,
- Banu Keerthana,
- Manu Vidhya Harikumar,
- Anupama Jyoti Kindo,
- T.K. Shruthi,
- Niranjan Ragavan,
- Julius Xavier Scott
Affiliations
- Dhaarani Jayaraman
- Department of Paediatric Hematology and Oncology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India; Corresponding author. Department of Pediatric Hematology and Oncology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India.
- Harshavardhan Mahalingam
- Department of Radiodiagnosis, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Naga Geetha Rani Mangam
- Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Swati Narasimhan
- Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Padmasani Venkat Ramanan
- Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- K. Stephen Sudhakar
- Department of Ophthalmology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Prasanna Kumar S
- Department of Otolaryngology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Banu Keerthana
- Department of Pathology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Manu Vidhya Harikumar
- Department of Dermatology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Anupama Jyoti Kindo
- Department of Microbiology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- T.K. Shruthi
- Department of Pediatric Critical Care, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Niranjan Ragavan
- Department of Paediatrics, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Julius Xavier Scott
- Department of Paediatric Hematology and Oncology, Sri Ramachandra Institute of Higher Education and Research, No.1, Ramachandra Nagar, Porur, Chennai, 600116, India
- Journal volume & issue
-
Vol. 9,
no. 4
pp. 271 – 273
Abstract
Mucormycosis is a dreaded condition with high mortality rates noted in immunocompromised hosts. Though iron overload is a known risk factor, children with transfusion-dependent thalassemia have been rarely reported with invasive mucormycosis. We present an 8-year-old girl with transfusion-dependent thalassemia with hypersplenism and iron overload. She had invasive rhino-sino-orbital mucormycosis with a fatal outcome despite aggressive surgical and medical management.
