Ru(phen)3Cl2‐Catalyzed Chlorotrifluoromethylation of Unactivated Alkenes
Wenhao Su,
Jing Cui,
Prof. Dr. Runsheng Zeng
Affiliations
Wenhao Su
Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China
Jing Cui
Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China
Prof. Dr. Runsheng Zeng
Key Laboratory of Organic Synthesis of Jiangsu Province College of Chemistry Chemical Engineering and Materials Science Soochow University Suzhou 215123 P. R. China
Abstract A novel Ru(phen)3Cl2‐catalyzed free‐radical chlorotrifluoromethylation reaction of unactivated olefins was investigated. Substituted 8‐aminoquinoline‐derived inert enamides were reacted with the Togni regent to afford a broad range of Cl‐containing trifluoromethyl derivatives in good yields. The reaction proceeded at 90 °C and experimental result shows that the chlorine source of the products originated from LiCl.
