Emerging Infectious Diseases (May 2021)

Severe Case of Rickettsiosis Identified by Metagenomic Sequencing, China

  • Zhongqiu Teng,
  • Yan Shi,
  • Yao Peng,
  • Huayi Zhang,
  • Xia Luo,
  • Xinchang Lun,
  • Lianxu Xia,
  • Yuanhai You,
  • Zhenpeng Li,
  • Wen Zhang,
  • Ying Zhang,
  • Shicun Dong,
  • Wentao Guo,
  • Biao Kan,
  • Bo Pang,
  • Jianguo Xu,
  • Aiping Qin

DOI
https://doi.org/10.3201/eid2705.203265
Journal volume & issue
Vol. 27, no. 5
pp. 1530 – 1532

Abstract

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A case of Rickettsia sibirica subspecies sibirica BJ-90 infection in China was identified by metagenomic analysis of an eschar biopsy specimen and confirmed by nested PCR. Seroprevalence of spotted fever group Rickettsia was ≈17.4% among the local population. This report highlights the threat of rickettsioses to public health in the Qinghai–Tibet Plateau.

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