Acute myeloid leukemia-driven IL-3-dependent upregulation of BCL2 in non-malignant hematopoietic stem and progenitor cells increases venetoclax-induced cytopenias
Dominic J. Fowler-Shorten,
Rebecca S. Maynard,
Katherine Hampton,
Annalisa Altera,
Matthew Markham,
Martha Ehikioya,
Edyta E. Wojtowicz,
Kristian M. Bowles,
Stuart A. Rushworth,
Charlotte Hellmich
Affiliations
Dominic J. Fowler-Shorten
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Rebecca S. Maynard
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Katherine Hampton
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Annalisa Altera
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Matthew Markham
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Martha Ehikioya
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Edyta E. Wojtowicz
Earlham Institute, Norwich Research Park, Norwich, NR4 7UH
Kristian M. Bowles
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ, United Kingdom; Department of Haematology, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY
Stuart A. Rushworth
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ
Charlotte Hellmich
Norwich Medical School, University of East Anglia, Norwich Research Park, Norwich, NR4 7UQ, United Kingdom; Department of Haematology, Norfolk and Norwich University Hospital NHS Trust, Colney Lane, Norwich, NR4 7UY
