Genome sequencing and annotation of multidrug resistant Mycobacterium tuberculosis (MDR-TB) PR10 strain
Mohd Zakihalani A. Halim,
Mohammad Maaruf Jaafar,
Lay Kek Teh,
Mohamad Izwan Ismail,
Lian Shien Lee,
Yun Fong Ngeow,
Norazmi Mohd Nor,
Zainul Fadziruddin Zainuddin,
Thean Hock Tang,
Mohd Nazalan Mohd Najimudin,
Mohd Zaki Salleh
Affiliations
Mohd Zakihalani A. Halim
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia
Mohammad Maaruf Jaafar
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia
Lay Kek Teh
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Selangor, Malaysia
Mohamad Izwan Ismail
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia
Lian Shien Lee
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia
Yun Fong Ngeow
Faculty of Medicine & Health Sciences, Universiti Tunku Abdul Rahman, Malaysia
Norazmi Mohd Nor
School of Health Sciences, Health Campus, Universiti Sains Malaysia, Malaysia; Institute for Research in Molecular Medicine (INFORMM), Universiti Sains Malaysia, Malaysia
Zainul Fadziruddin Zainuddin
School of Health Sciences, Health Campus, Universiti Sains Malaysia, Malaysia; Business and Technopreneur Development Division, Malaysian Technology Development Corporation (MTDC) Sdn. Bhd, Malaysia
Thean Hock Tang
Advanced Medical and Dental Institute (AMDI), Universiti Sains Malaysia, Malaysia
Mohd Nazalan Mohd Najimudin
School of Biological Sciences, Universiti Sains Malaysia, Malaysia
Mohd Zaki Salleh
Integrative Pharmacogenomics Institute (iPROMISE), Universiti Teknologi MARA (UiTM), Malaysia; Faculty of Pharmacy, Universiti Teknologi MARA (UiTM), Selangor, Malaysia; Corresponding author.
Here, we report the draft genome sequence and annotation of a multidrug resistant Mycobacterium tuberculosis strain PR10 (MDR-TB PR10) isolated from a patient diagnosed with tuberculosis. The size of the draft genome MDR-TB PR10 is 4.34 Mbp with 65.6% of G + C content and consists of 4637 predicted genes. The determinants were categorized by RAST into 400 subsystems with 4286 coding sequences and 50 RNAs. The whole genome shotgun project has been deposited at DDBJ/EMBL/GenBank under the accession number CP010968. Keywords: Mycobacterium tuberculosis, Genome, MDR, Extrapulmonary