Journal of Applied Pharmaceutical Research (Mar 2021)

Evaluation of analgesic and anti-inflammatory activity of ethanolic extract of Enhydra fluctuans on male wistar rats

  • Kishor Kumar Roy,
  • Md. Kabirul Islam Mollah,
  • Md. Masud Reja,
  • Dibyendu Shil,
  • Ranjan Kumar Maji

DOI
https://doi.org/10.18231/JOAPR.2021.9.1.37.42
Journal volume & issue
Vol. 9, no. 1
pp. 37 – 42

Abstract

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Enhydra fluctuations an edible semi-aquatic vegetable plant are widely used in the traditional system of medicine. Ethanolic extract of Enhydra fluctuans was screened for analgesic & anti-inflammatory activity. Analgesic activity was evaluated by the hot plate method and anti-inflammatory activity was evaluated by formalin induce paw edema in Wistar rats (male). Ethanolic extract dose of 300 mg/kg reduce formalin induce paw inflammation and also increased the pain threshold in rats evidenced by hot plate method. The experimental results concluded that Enhydra fluctuans have significant analgesic and anti-inflammatory activity may due to flavonoid and phenolic compound content.

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