Radioprotective effects of melanin-glucan complex from Fomes Fomentarius and indralin at irradiation of mice BALB/C by dose of 5,95 Gy/8,5 min

Abstract

Protective effect of melanin-glucan complex from F. fomentarius (MGC) and Russian armed forces radiopro-tector indralin in the model of acute exposure by dose of 5.95 Gy/8.5min care is compared. Obtained results indi-cate availabi¬lity at MGC and indralin both direct and indirect "bystander effect” of DNA-protective properties, as well as severe anxiolytic activity. Thus for indralin protection factor was 0.33 when in MGC it was 2.3 times higher (0.75).

Keywords

• ionizing radiation
• acute exposure
• protection coefficient
• DNA single-strand breaks
• mushroom biopo-lymers
• indralin
• "bystander effect"
• behavioral responses