mSphere (Feb 2021)
Interplay of Antibody and Cytokine Production Reveals CXCL13 as a Potential Novel Biomarker of Lethal SARS-CoV-2 Infection
- Alexander M. Horspool,
- Theodore Kieffer,
- Brynnan P. Russ,
- Megan A. DeJong,
- M. Allison Wolf,
- Jacqueline M. Karakiozis,
- Brice J. Hickey,
- Paolo Fagone,
- Danyel H. Tacker,
- Justin R. Bevere,
- Ivan Martinez,
- Mariette Barbier,
- Peter L. Perrotta,
- F. Heath Damron
Affiliations
- Alexander M. Horspool
- ORCiD
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Theodore Kieffer
- Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USA
- Brynnan P. Russ
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Megan A. DeJong
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- M. Allison Wolf
- ORCiD
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Jacqueline M. Karakiozis
- Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USA
- Brice J. Hickey
- Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USA
- Paolo Fagone
- Department of Biochemistry, West Virginia University, Morgantown, West Virginia, USA
- Danyel H. Tacker
- Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USA
- Justin R. Bevere
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Ivan Martinez
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Mariette Barbier
- ORCiD
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- Peter L. Perrotta
- Department of Pathology, Anatomy and Laboratory Medicine, West Virginia University School of Medicine, Morgantown, West Virginia, USA
- F. Heath Damron
- ORCiD
- Department of Microbiology, Immunology, and Cell Biology, West Virginia University, Morgantown, West Virginia, USA
- DOI
- https://doi.org/10.1128/mSphere.01324-20
- Journal volume & issue
-
Vol. 6,
no. 1
Abstract
The SARS-CoV-2 pandemic is continuing to impact the global population, and knowledge of the immune response to COVID-19 is still developing. This study assesses the interplay of different parts of the immune system during COVID-19 disease.
