Frontiers in Chemistry (Dec 2021)

Cyclohexanohemicucurbit[8]uril Inclusion Complexes With Heterocycles and Selective Extraction of Sulfur Compounds From Water

  • Tatsiana Shalima,
  • Kamini A. Mishra,
  • Sandra Kaabel,
  • Lukas Ustrnul,
  • Simona Bartkova,
  • Kaia Tõnsuaadu,
  • Ivo Heinmaa,
  • Riina Aav

DOI
https://doi.org/10.3389/fchem.2021.786746
Journal volume & issue
Vol. 9

Abstract

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Solid-phase extraction that utilizes selective macrocyclic receptors can serve as a useful tool for removal of chemical wastes. Hemicucurbiturils are known to form inclusion complexes with suitably sized anions; however, their use in selective binding of non-charged species is still very limited. In this study, we found that cyclohexanohemicucurbit[8]uril encapsulates five- and six-membered sulfur- and oxygen-containing unsubstituted heterocycles, which is investigated by single-crystal X-ray diffraction, NMR spectroscopy, isothermal titration calorimetry, and thermogravimetry. The macrocycle acts as a promising selective sorption material for the extraction of sulfur heterocycles, such as 1,3-dithiolane and α-lipoic acid, from water.

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