Novel Variant of Tickborne Encephalitis Virus, Russia

Abstract

We isolated a novel strain of tickborne encephalitis virus (TBEV), Glubinnoe/2004, from a patient with a fatal case in Russia. We sequenced the strain, whose landmark features included 57 amino acid substitutions and 5 modified cleavage sites. Phylogenetically, Glubinnoe/2004 is a novel variant that belongs to the Eastern type of TBEV.

Keywords

• Tickborne encephalitis virus
• TBEV
• flavivirus
• genotyping
• polyprotein sequence
• human lethal cases