Empirical identification and validation of tumor-targeting T cell receptors from circulation using autologous pancreatic tumor organoids

• Qingda Meng,
• Shanshan Xie,
• Ling Huang,
• Manuel Hidalgo,
• Joseph Grossman,
• G Kenneth Gray,
• Mohammad H Dezfulian,
• Weilin Li,
• Dipikaa Akshinthala,
• Elizabeth Ferrer,
• Catherine Conahan,
• Sofia Perea Del Pino,
• Stephen J Elledge,
• Senthil K Muthuswamy

Affiliations

Qingda Meng

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Shanshan Xie

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Ling Huang

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Manuel Hidalgo

Division of Hematology and Medical Oncology, Weill Cornell Medicine, New York, New York, USA

Joseph Grossman

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

G Kenneth Gray

Department of Cell Biology, Harvard Medical School, Boston, Massachusetts, USA

Mohammad H Dezfulian

Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA

Weilin Li

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Dipikaa Akshinthala

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Elizabeth Ferrer

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Catherine Conahan

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Sofia Perea Del Pino

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA

Stephen J Elledge

Department of Genetics, Harvard Medical School, Boston, Massachusetts, USA

Senthil K Muthuswamy

Department of Medicine, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, Massachusetts, USA