Discover Oncology (May 2024)

Advances in the molecular regulation mechanism of tumor dormancy and its therapeutic strategy

  • Yuan Wang,
  • Linlin Wang,
  • Yaojun Wei,
  • Chuang Wei,
  • Haohang Yang,
  • Qiurui Chen,
  • Rongxin Zhang,
  • Han Shen

DOI
https://doi.org/10.1007/s12672-024-01049-2
Journal volume & issue
Vol. 15, no. 1
pp. 1 – 19

Abstract

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Abstract Tumor dormancy is a stage in the growth and development of malignant cells and is one of the biological characteristics of malignant cells. Complex transitions involving dormant tumor cells between quiescent and proliferative states pose challenges for tumor eradication. This paper explores the biological features and molecular mechanisms of tumor dormancy and highlights emerging therapies. The strategies discussed promise innovative clinical potential against malignant tumors. Understanding the mechanisms of dormancy can help provide valuable insights into the diagnosis and treatment of malignant tumors to advance the fight against this world problem.

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