Nature Communications (Feb 2016)

Periodic patterning of the Drosophila eye is stabilized by the diffusible activator Scabrous

  • Avishai Gavish,
  • Arkadi Shwartz,
  • Abraham Weizman,
  • Eyal Schejter,
  • Ben-Zion Shilo,
  • Naama Barkai

DOI
https://doi.org/10.1038/ncomms10461
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 10

Abstract

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Patterning in the Drosophila eye is achieved by a series of signalling cascades over several cell distances. Here Gavish et al.model lateral inhibition in the developing eye to understand how developmental noise refines such patterning, identifying a novel activator required for buffering spatial variability.