Медицинская иммунология (Jul 2014)

IN VITRO IMMUNOTROPICITY STUDIES OF POLYFUNCTIONAL WATER-SOLUBLE ANTIOXIDANTS

  • S. Yu. Klepikova,
  • O. P. Kolesnikova,
  • A. Ye. Prossenko,
  • N. V. Kandalintceva

DOI
https://doi.org/10.15789/1563-0625-2008-2-3-269-272
Journal volume & issue
Vol. 10, no. 2-3
pp. 269 – 272

Abstract

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Abstract. A study of immunotropic properties of ω-(3,5-dimethyl-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-11-7), and ω-(3,5-di-tret-butil-4-hydroxyphenyl) propylthiosulfonate, sodium salt (F-17-7) was carried out, employing an in vitro model of spontaneous and mitogen- stimulated proliferation of cultured spleen cells. It is revealed, that the F-11-7 and F-17-7 compounds are able to suppress proliferation of intact splenocytes in a dose-dependent manner. (Med. Immunol., 2008, vol. 10, n 2-3, pp 269-272).

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