P446: COMPREHENSIVE CHARACTERIZATION OF DIFFERENTIAL GENE EXPRESSION AND ISOFORM USAGE IN SPLICING FACTOR-MUTATED ACUTE MYELOID LEUKEMIA USING LONG-READ SEQUENCING

• Susanne Thieme,
• Alexander Graf,
• Stefan Krebs,
• Helmut Blum,
• Maria Solovey,
• Frank Ziemann,
• Jonathan Christ,
• Maja Rothenberg-Thurley,
• Annika Dufour,
• Stephanie Schneider,
• Maria Cristina Sauerland,
• Dennis Görlich,
• Utz Krug,
• Wolfgang E. Berdel,
• Bernhard Wörmann,
• Wolfgang Hiddemann,
• Jan Braess,
• Karsten Spiekermann,
• Klaus Metzeler,
• Ulrich Mannsmann,
• Tobias Herold

Affiliations

Susanne Thieme

1 Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU, Munich, Germany

Alexander Graf

1 Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU, Munich, Germany

Stefan Krebs

1 Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU, Munich, Germany

Helmut Blum

1 Laboratory for Functional Genome Analysis (LAFUGA), Gene Center, LMU, Munich, Germany

Maria Solovey

2 Biomedical Center (BMC), Physiological Chemistry, Faculty of Medicine, LMU Munich, Planegg-Martinsried, Germany

Frank Ziemann

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Jonathan Christ

4 Institute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany

Maja Rothenberg-Thurley

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Annika Dufour

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Stephanie Schneider

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Maria Cristina Sauerland

6 Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

Dennis Görlich

6 Institute of Biostatistics and Clinical Research, University of Münster, Münster, Germany

Utz Krug

7 Department of Medicine 3, Klinikum Leverkusen, Leverkusen, Germany

Wolfgang E. Berdel

8 Department of Medicine, Hematology and Oncology, University of Münster, Münster, Germany

Bernhard Wörmann

9 German Society of Hematology and Oncology, Berlin; (9) Department of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany

Wolfgang Hiddemann

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Jan Braess

10 Department of Oncology and Hematology, Hospital Barmherzige Brüder, Regensburg, Germany

Karsten Spiekermann

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany

Klaus Metzeler

11 Medical Clinic and Policlinic I, Hematology and Cellular Therapy, Leipzig University Hospital, Leipzig, Germany

Ulrich Mannsmann

4 Institute for Medical Information Processing, Biometry and Epidemiology, LMU Munich, Munich, Germany

Tobias Herold

3 Department of Medicine III, University Hospital, LMU Munich, Munich, Germany