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Clinical observation of ocular alkali burn by Breviscapinun

Guoji Yanke Zazhi. 2014;14(7):1275-1277 DOI 10.3980/j.issn.1672-5123.2014.07.28

 

Journal Homepage

Journal Title: Guoji Yanke Zazhi

ISSN: 1672-5123 (Print)

Publisher: Press of International Journal of Ophthalmology (IJO PRESS)

Society/Institution: Chinese Medical Association Xi’an Branch

LCC Subject Category: Medicine: Ophthalmology

Country of publisher: China

Language of fulltext: English

Full-text formats available: PDF

 

AUTHORS


Yu-Lian Cai (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

Yang-Chun Xie (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

Rong Su (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

Dao-Wei Qian (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

Lan Wu (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

Jian-Jun Yue (Department of Ophthalmology, Pingshan New District People's Hospital of Shenzhen, Shenzhen 518118, Guangdong Province, China)

EDITORIAL INFORMATION

Double blind peer review

Editorial Board

Instructions for authors

Time From Submission to Publication: 24 weeks

 

Abstract | Full Text

AIM: To find better ways of treating ocular alkali burn, and to reduce the suffering of patients and social burden.<p>METHODS:Totally 100 patients were graded according to the degree of chemical burns to four major groups, each half were randomly divided into the control group and the treatment group. Control group underwent conventional treatment. In addition to conventional therapy, patients in each treatment group were also added a Breviscapine intravenous injection of 40mg daily. Corneal recovery time, changes in vision, degree of corneal opacity, number of corneal neovascularization and other complications were observed. Curative effects were analyzed statistically. <p>RESULTS: There was no significant difference in level Ⅰ group between control group and treatment group(<i>P</i>>0.05); There were significantly different in level Ⅱ, Ⅲ and Ⅳ group(<i>P</i><0.05). Compared to the degree of corneal opacity and the number of corneal neovascularization, the treatment group was obviously better than the control group(<i>P</i><0.05).<p>CONCLUSION: Breviscapine in the treatment of ocular alkali burns can shorten the course of treatment, reduce corneal scarring, and improve vision.