Sequential cellular niches control the generation of enucleated erythrocytes from human pluripotent stem cells

• Jun Shen,
• Yaoyao Zhu,
• Cuicui Lyu,
• Zicen Feng,
• Shuzhen Lyu,
• Yuping Zhao,
• Dixie L. Hoyle,
• Guangzhen Ji,
• Weimin Miao,
• Xiaobing Zhang,
• Linzhao Cheng,
• Robert A. Brodsky,
• Tao Cheng,
• Zack Z. Wang

Affiliations

Jun Shen

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China;Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Yaoyao Zhu

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Cuicui Lyu

Department of Hematology, the First Central Hospital of Tianjin, Tianjin, China

Zicen Feng

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Shuzhen Lyu

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Yuping Zhao

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Dixie L. Hoyle

Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Guangzhen Ji

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China

Weimin Miao

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China;Tianjin Key Laboratory of Blood Cell Therapy and Technology, Tianjin, China

Xiaobing Zhang

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China;Department of Medicine, Loma Linda University, Loma Linda, CA, USA

Linzhao Cheng

Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Robert A. Brodsky

Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA

Tao Cheng

State Key Laboratory of Experimental Hematology, Institute of Hematology & Blood Diseases Hospital, Chinese Academy of Medical Sciences & Peking Union Medical College, Tianjin, China;Center for Stem Cell Medicine, Chinese Academy of Medical Sciences, Tianjin, China;Department of Stem Cell & Regenerative Medicine, Peking Union Medical College, Tianjin, China

Zack Z. Wang

Division of Hematology, Johns Hopkins University School of Medicine, Baltimore, MD, USA