Evaluation of Chronic Kidney Disease Risk Factors after Radical Nephrectomy

Abstract

Intraoperative hypotension (IOH) and loss of blood during radical nephrectomy (RN) cause postoperative clinically significant renal dysfunction, which after 12 months can cause a reduction in serum creatinine clearance of p p t-test revealed that only clinically significant AKI had a main effect (g = −1.08, p p = 0.02, and contralateral kidney CT volume (OR 0.97, p = 0.04) had a clinically significantly decreased risk of postoperative CKD. Risk factors of AKI with CKD upstage were a small contralateral kidney CT volume (OR 46.70), NLR > 3.5 (OR 1.42), higher primary eGFR (OR 1.13) and longer IOH (OR 1.05), and for all of these, p 3.5. A higher preoperative eGFR and contralateral kidney CT volume reduces the risk of postoperative CKD.

Keywords

• radical nephrectomy
• intraoperative hypotension
• blood loss
• chronic kidney disease
• clinically significant acute kidney injury