Study of the Qualitative Composition and Quantitative Content of Parthenolide in the Feverfew (Tanacetum Parthenium) Herb Cultivated in Ukraine

Hordiei K. R.; Gontova T. N.; Gubar S. N.; Yaremenko M. S.; Kotova E. E.

doi:10.2478/afpuc-2020-0011

European Pharmaceutical Journal (Jan 2021)

Study of the Qualitative Composition and Quantitative Content of Parthenolide in the Feverfew (Tanacetum Parthenium) Herb Cultivated in Ukraine

Hordiei K. R.,
Gontova T. N.,
Gubar S. N.,
Yaremenko M. S.,
Kotova E. E.

Affiliations

Hordiei K. R.: Department of pharmaceutical botany, National University of Pharmacy, 4 Valentinivska st., Kharkiv, Ukraine
Gontova T. N.: Department of pharmaceutical botany, National University of Pharmacy, 4 Valentinivska st., Kharkiv, Ukraine
Gubar S. N.: Department of pharmaceutical chemistry, National University of Pharmacy, 4 Valentinivska st., Kharkiv, Ukraine
Yaremenko M. S.: Department of pharmaceutical botany, National University of Pharmacy, 4 Valentinivska st., Kharkiv, Ukraine
Kotova E. E.: Ukrainian Scientific Pharmacopoeial Center for Quality of Medicines, 33 Astronomichna St., Kharkiv, Ukraine

DOI: https://doi.org/10.2478/afpuc-2020-0011
Journal volume & issue: Vol. 67, no. 2
pp. 27 – 33

Abstract

Read online

Feverfew is a well-known medicinal plant as a source of the sesquiterpene lactones, the main one is a parthenolide (about 85%). Owing to the parthenolide, feverfew herb has anti-inflammatory activity and it is widely used for prevention of migraine. The aim was to study the qualitative composition and quantitative content of the parthenolide in the samples of the feverfew herb cultivated in Ukraine and to study the influence of environmental factors on the accumulation of parthenolide.

Published in European Pharmaceutical Journal

ISSN: 2453-6725 (Online)
Publisher: Sciendo
Country of publisher: Poland
LCC subjects: Medicine: Therapeutics. Pharmacology
Website: https://sciendo.com/journal/AFPUC

About the journal

Abstract

Keywords