Surface Effect of Nano-Roughened Yttria-Doped Zirconia on Salivary Protein Adhesion

Abstract

Biocompatibility of yttria (3 mol%) stabilized zirconia ceramics, 3Y-TZP, was affected to a large degree as a result of protein adsorption from human saliva that in turn depends on materials surface properties. Variable nano-roughness levels in 3Y-TZP discs were characterized and tested for specificity and selectivity with respect to size and uptake for human salivary protein.

Keywords

• 3 mol% yttria partially stabilized zirconia ceramics (3Y-TZP)
• saliva
• nano-surface roughness
• protein adsorption
• alpha-amylase adsorption