Antibiotics (Apr 2022)

Peri-Operative Prophylaxis in Patients of Neonatal and Pediatric Age Subjected to Cardiac and Thoracic Surgery: A RAND/UCLA Appropriateness Method Consensus Study

  • Sonia Bianchini,
  • Laura Nicoletti,
  • Sara Monaco,
  • Erika Rigotti,
  • Agnese Corbelli,
  • Annamaria Colombari,
  • Cinzia Auriti,
  • Caterina Caminiti,
  • Giorgio Conti,
  • Maia De Luca,
  • Daniele Donà,
  • Luisa Galli,
  • Silvia Garazzino,
  • Alessandro Inserra,
  • Stefania La Grutta,
  • Laura Lancella,
  • Mario Lima,
  • Andrea Lo Vecchio,
  • Gloria Pelizzo,
  • Nicola Petrosillo,
  • Giorgio Piacentini,
  • Carlo Pietrasanta,
  • Nicola Principi,
  • Matteo Puntoni,
  • Alessandro Simonini,
  • Simonetta Tesoro,
  • Elisabetta Venturini,
  • Annamaria Staiano,
  • Fabio Caramelli,
  • Gaetano Domenico Gargiulo,
  • Susanna Esposito,
  • on behalf of the Peri-Operative Prophylaxis in Neonatal and Paediatric Age (POP-NeoPed) Study Group

DOI
https://doi.org/10.3390/antibiotics11050554
Journal volume & issue
Vol. 11, no. 5
p. 554

Abstract

Read online

Surgical site infections (SSIs) represent a potential complication of surgical procedures, with a significant impact on mortality, morbidity, and healthcare costs. Patients undergoing cardiac surgery and thoracic surgery are often considered patients at high risk of developing SSIs. This consensus document aims to provide information on the management of peri-operative antibiotic prophylaxis for the pediatric and neonatal population undergoing cardiac and non-cardiac thoracic surgery. The following scenarios were considered: (1) cardiac surgery for the correction of congenital heart disease and/or valve surgery; (2) cardiac catheterization without the placement of prosthetic material; (3) cardiac catheterization with the placement of prosthetic material; (4) implantable cardiac defibrillator or epicardial pacemaker placement; (5) patients undergoing ExtraCorporal Membrane Oxygenation; (6) cardiac tumors and heart transplantation; (7) non-cardiac thoracic surgery with thoracotomy; (8) non-cardiac thoracic surgery using video-assisted thoracoscopy; (9) elective chest drain placement in the pediatric patient; (10) elective chest drain placement in the newborn; (11) thoracic drain placement in the trauma setting. This consensus provides clear and shared indications, representing the most complete and up-to-date collection of practice recommendations in pediatric cardiac and thoracic surgery, in order to guide physicians in the management of the patient, standardizing approaches and avoiding the abuse and misuse of antibiotics.

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