299 Broad T antigen-specific CD8+ T cell repertoire is associated with response to PD-1 blockade in virus positive merkel cell carcinoma

• Paul Nghiem,
• Suzanne Topalian,
• Steven Fling,
• Nirasha Ramchurren,
• Candice Church,
• Ulla Hansen,
• Amalie Bentzen,
• Sine Hadrup

Affiliations

Paul Nghiem

Division of Dermatology, University of Washington Medical Center at South Lake Union, Seattle, Washington, USA

Suzanne Topalian

Aff230 grid.21107.350000000121719311Department of Surgery, Johns Hopkins University School of Medicine, Sidney Kimmel Comprehensive Cancer Center, and Bloomberg-Kimmel Institute for Cancer Immunotherapy Baltimore MD USA

Steven Fling

Aff233 grid.34477.330000000122986657University of Washington Seattle WA USA

Nirasha Ramchurren

Fred Hutchinson Cancer Research Center, Seattle, Washington, USA

Candice Church

University of Washington, Seattle, Washington, USA

Ulla Hansen

1Technical University of Denmark, Kgs. Lyngby, Denmark

Amalie Bentzen

1Technical University of Denmark, Kgs. Lyngby, Denmark

Sine Hadrup

1Technical University of Denmark, Kgs. Lyngby, Denmark