Neurologia Medico-Chirurgica (Sep 2022)

Multimodal Management of Combined Posterior and Anterior Surgical Approach and Postoperative Pharmacological Therapy for Giant Cell Tumor of the Cervical Spine Encasing the Vertebral Artery: A Technical Case Report

  • Yuichiro TSUJI,
  • Yusuke FUKUO,
  • Takuya KANEMITSU,
  • Yoshihide KATAYAMA,
  • Ryokichi YAGI,
  • Ryo HIRAMATSU,
  • Masahiro KAMEDA,
  • Naosuke NONOGUCHI,
  • Motomasa FURUSE,
  • Shinji KAWABATA,
  • Ichiro BABA,
  • Toshihiro TAKAMI,
  • Masahiko WANIBUCHI

DOI
https://doi.org/10.2176/jns-nmc.2022-0158
Journal volume & issue
Vol. 62, no. 9
pp. 438 – 443

Abstract

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Giant cell tumor (GCT) of bone is essentially benign but locally aggressive, and the rate of local recurrence is high when the resection is not enough. En bloc resection is recommended as an ideal solution for GCT to decrease the risk of local recurrence, but it remains challenging for cervical GCT. In this technical case report, we present a case of extensively infiltrating GCT of the cervical spine completely encasing the vertebral artery (VA) on one side. The tumor was distributed to layers A-D, sectors 3-8 based on the Weinstein-Boriani-Biagini staging. Combined posterior and anterior surgical approach for the cervical spine was successfully performed and followed by postoperative adjuvant pharmacological therapy. This kind of multimodal management may be one of the solutions for advanced cervical GCT.

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