Онкогематология (Jul 2014)
Immune thrombocytopenia: clinical manifestation and therapy response. The interim analysis of Russian register of patients with primary immune thrombocytopenia and literature review
- I. A. Lisukov,
- A. A. Maschan,
- A. V. Shamardina,
- T. V. Chagorova,
- I. L. Davydkin,
- T. M. Sycheva,
- T. P. Zagoskina,
- E. V. Karyagina,
- G. N. Salogub,
- M. T. Savinova,
- T. V. Shelekhova,
- L. G. Kovaleva,
- T. V. Shneyder,
- A. N. Unzhekova,
- E. E. Kuznetsova,
- Yu. V. Shatokhin,
- M. O. Ivanova,
- E. Yu. Vinogradova,
- E. M. Volodicheva,
- I. V. Markova,
- O. V. Kanyukova,
- K. M. Abdulkadyrov,
- Yu. A. Sedlova,
- S. M. Osyunikhina,
- K. D. Kaplanov,
- N. V. Tsvetaeva,
- A. R. Akhmadeev,
- O. S. Uspenskaya,
- A. D. Kulagin,
- N. V. Medvedeva,
- A. G. Rumyantsev,
- B. V. Afanasiev
Affiliations
- I. A. Lisukov
- Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantation, St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- A. A. Maschan
- Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
- A. V. Shamardina
- Regional Children Clinical Hospital
- T. V. Chagorova
- Regional Oncologic Dispensary
- I. L. Davydkin
- Samara State Medical University, Ministry of Health of Russia
- T. M. Sycheva
- Alexander-and-Mary Regional Clinical Hospital
- T. P. Zagoskina
- Kirov Research Centre of Hematology and Transfusiology, Federal Medical Biological Agency
- E. V. Karyagina
- City Clinical Hospital № 15
- G. N. Salogub
- St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- M. T. Savinova
- City Clinical Hospital № 16
- T. V. Shelekhova
- Hematology Clinic, V.I. Razumovskiy Saratov State Medical University
- L. G. Kovaleva
- Hematological Research Centre, Ministry of Health of Russia
- T. V. Shneyder
- Leningrad Regional Clinical Hospital
- A. N. Unzhekova
- Perm Territorial Clinical Hospital
- E. E. Kuznetsova
- Regional Clinical Hospital
- Yu. V. Shatokhin
- Rostov State Medical University, Ministry of Health of Russia
- M. O. Ivanova
- I.P. Pavlov State Medical University, Ministry of Health of Russia
- E. Yu. Vinogradova
- Territorial Clinical Hospital
- E. M. Volodicheva
- Regional Clinical Hospital
- I. V. Markova
- Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantation, St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- O. V. Kanyukova
- Clinical Medical Unit № 1
- K. M. Abdulkadyrov
- Russian Research Institute of Hematology and Transfusiology, Russian Federal Medico-biological Agency
- Yu. A. Sedlova
- Regional Clinical Hospital
- S. M. Osyunikhina
- City Clinical Hospital № 4
- K. D. Kaplanov
- Regional Oncologic Clinical Dispensary № 1
- N. V. Tsvetaeva
- Hematological Research Centre, Ministry of Health of Russia
- A. R. Akhmadeev
- Republic Clinical Hospital
- O. S. Uspenskaya
- Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantation, St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- A. D. Kulagin
- Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantation, St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- N. V. Medvedeva
- City Hospital № 31
- A. G. Rumyantsev
- Dmitriy Rogachev Federal Research Center of Pediatric Hematology, Oncology and Immunology, Ministry of Health of Russia
- B. V. Afanasiev
- Raisa Gorbacheva Memorial Institute of Children Hematology and Transplantation, St.-Petersburg I.P. Pavlov State Medical University, Ministry of Health of Russia
- DOI
- https://doi.org/10.17650/1818-8346-2013-8-2-61-69
- Journal volume & issue
-
Vol. 8,
no. 2
pp. 61 – 69
Abstract
Primary immune thrombocytopenia (ITP) is a rare (orphan) blood disease. Most frequent manifestations of ITP are purpura, petechiae and bleedings with many patients have either no symptoms or minimal bleedings manifestation. The management of ITP varies widely and must be based on current international recommendations and individual assessment of clinical course. The paper presents the results of interim analysis of clinical course and therapeutic approaches in the Russian register of ITP patients with immune thrombocytopenia and literature review about ITP treatment approaches.
Keywords