Nature Communications (Sep 2018)

"RETRACTED ARTICLE: Vibrio parahaemolyticus RhsP represents a widespread group of pro-effectors for type VI secretion systems

  • Nan Jiang,
  • Le Tang,
  • Ruiqiang Xie,
  • Zhi Li,
  • Brianne Burkinshaw,
  • Xiaoye Liang,
  • Dylan Sosa,
  • L. Aravind,
  • Tao Dong,
  • Dapeng Zhang,
  • Jun Zheng

DOI
https://doi.org/10.1038/s41467-018-06201-5
Journal volume & issue
Vol. 9, no. 1
pp. 1 – 14

Abstract

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It is unclear how Rhs toxins lacking a PAAR motif are secreted by Type VI secretion systems. Here, the authors show for one of these proteins that the mechanism requires removal of an N-terminal fragment by auto-proteolysis, followed by interaction with a PAAR protein and then secretion.