Gender-Based Differences Of D-Dimer Levels Among Mild COVID-19 Patients Living In The Erbil City-Iraq.

Abstract

SARS-CoV-2, the causative agent of severe acute respiratory syndrome, possesses the capability to induce respiratory illness, which leads to thrombotic diseases. One of the potential biomarkers associated with the poor prognosis in COVID-19 is the rise of D-dimer. However, the potential of plasma's D-dimer to predict gender disparities in disease severity remains undetermined in Erbil-Iraq. This study aimed to evaluate the gender-based difference of the D-dimer in mild males and females of COVID-19 patients; their correlation with age was also within the scope of this study. Retrospectively analyzed laboratory and clinical data of mild COVID-19 cases confirmed at Bio Lab in Erbil, Kurdistan Region of Iraq. An immunofluorescence assay was used to measure the amount of D-dimer in 1174 patients. The results were given in fibrinogen equivalent units (µg/ml). Out of 1174, 591 (50.34%) were male. Their mean age was (52.23 ± 0.657); while 583 (49.66%) were female, their mean age was (51.11 ± 0.722). The mean D-dimer among male patients was 1.163 μg/ml (±0.175 μg/ml), whereas the level of D-dimer in female patients was equal to 1.172 μg/ml (±0.147 μg/ml). The study finds a correlation between age and D-dimer. In conclusion, there is no significant difference in D-dimer value between the male and female COVID-19 groups.

Keywords

• keywords: covid-19; d-dimer; gender; and thrombotic disorders