European Journal of Medical Research (Feb 2022)

Low-dose radiation treatment for painful plantar enthesophyte: a highly effective therapy with little side effects

  • Freddy Djiepmo,
  • Bálint Tamaskovics,
  • Edwin Bölke,
  • Matthias Peiper,
  • Jan Haussmann,
  • Judith Neuwahl,
  • Danny Jazmati,
  • Kitti Maas,
  • Livia Schmidt,
  • Roman Gelzhäuser,
  • Christoph Schleich,
  • Stefanie Corradini,
  • Klaus Orth,
  • Martijn van Griensven,
  • Amir Rezazadeh,
  • Kimia Karimi,
  • Wilfried Budach,
  • Christiane Matuschek

DOI
https://doi.org/10.1186/s40001-022-00642-x
Journal volume & issue
Vol. 27, no. 1
pp. 1 – 11

Abstract

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Abstract Aim Plantar enthesophyte is a common degenerative disorder. Surgical and medical treatment options are associated with either poor outcome or high percentage of relapse. Observations have indicated a beneficial effect of radiation therapy. We therefore wanted to evaluate pain reduction using orthovolt or cobalt-based radiation treatment for painful plantar enthesophyte and determine long-term response as well as prognostic parameters in this condition. Methods We identified a total of 102 consecutive patients treated for a total of 117 symptomatic heel spurs. 59 patients were treated with cobalt radiation, 31 patients with orthovolt therapy and 12 patients with both radiation systems. Primary outcome measure was pain reduction being scored using the modified Rowe Score prior therapy, at the end of each treatment series as well as after 6 weeks. Secondary outcome measure was long-term outcome, evaluated in patients with a follow-up period of longer than 3 years. Results Before radiation therapy, 61 patients (60.4%) had a score of 0, significant strong pain. At the time of completion of radiation treatment, 3 patients (2.7%) were pain-free (score of 30), whereas 8 patients (7.9%) had still severe pain (score 0). 6 weeks after radiation therapy, 33 patients (32.7%) were pain-free and 8 patients (7.9%) had severe pain (score 0), while at the time data of collection, 74 patients (73%) were free of pain and 1 patient (1%) had strong pain (score 0). Duration of pain before the start of radiation treatment was a significant prognostic factor (p = 0.012) for response to treatment. Conclusion Radiotherapy of painful plantar enthesophyte is a highly effective therapy with little side effects providing long-term therapeutic response. The only significant prognostic parameter for response to treatment is the duration of pre-radiation therapy pain. Early integration of radiation therapy in the treatment seems to result in superior pain reduction.

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