Evaluation of the role of dynamic 64-MDCT in the characterization and work up of breast cancer

Abstract

Background: Imaging of the breast is a vital component not only for breast cancer screening, but also for diagnosis and treatment. Dynamic MDCT has a very promising role as diagnostic tool in breast cancer patients. Objective: This study aimed to emphasize the role of 64 MDCT in the work up of breast cancer. Patients and methods: Between October 2012 to April 2014, 100 consecutive patients with suspicious breast lesions underwent bilateral mammography, breast ultrasound and dynamic MDCT. We evaluated the primary lesion morphology, pattern of enhancement with the time enhancement curve, extensions, lymph nodal status, and metastasis in lung or chest wall. Tumor staged based on the TNM classification. Results: In the studied 100 patients, MDCT detects 107 mass lesions; 64 were malignant and 43 were benign. The collected imaging data were correlated with the surgical and pathologic findings in all patients. Breast dynamic MDCT with the pattern of the time enhancement curve was found to be accurate in diagnosing and lesion characterization, the sensitivity was 93%, specificity was 89%, and accuracy was 91%. Conclusion: Dynamic MDCT should be considered as a feasible non invasive imaging tool for the diagnosis and work up in patients with breast cancer.

Keywords

• 64-MDCT breast cancer diagnosis