Physiological adaptations during weaning from veno-venous extracorporeal membrane oxygenation

Abstract

Take home message Successful weaning from veno-venous ECMO requires understanding and consideration of the complex physiological interactions between the native and the extracorporeal lung. We describe our understanding of the physiological adaptations of the patient as extracorporeal support is weaned and outline the implications for clinical practice.

Keywords

• Extracorporeal membrane oxygenation (ECMO)
• Weaning
• Acute respiratory distress syndrome (ARDS)
• Respiratory drive
• Patient self-inflicted lung injury (P-SILI)