Imaging diagnostic features of intracranial primary extranodal Rosai-Dorfman disease: Two case reports and literature review

Gan Cao, MD; Shanghuang Xie, MD; Mifang Li, MD; Xiaolin Yang, MD; Jichao Zhu, MD; Lingyan Zhang, PhD

Radiology Case Reports (Jun 2023)

Imaging diagnostic features of intracranial primary extranodal Rosai-Dorfman disease: Two case reports and literature review

Gan Cao, MD,
Shanghuang Xie, MD,
Mifang Li, MD,
Xiaolin Yang, MD,
Jichao Zhu, MD,
Lingyan Zhang, PhD

Affiliations

Gan Cao, MD: Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China
Shanghuang Xie, MD: Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China
Mifang Li, MD: Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China
Xiaolin Yang, MD: Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China
Jichao Zhu, MD: Corresponding authors.; Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China
Lingyan Zhang, PhD: Corresponding authors.; Department of Medical Imaging, Longgang Central Hospital of Shenzhen, 6082 Longgang Avenue, Longgang District, Shenzhen, 518000, China

Journal volume & issue: Vol. 18, no. 6
pp. 2165 – 2171

Abstract

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In this report, we describe 2 cases of rare intracranial extranodal Rosai-Dorfman disease. The occurrence of this type of non-Langerhans cell histiocytosis in the central nervous system is infrequent, with less than 5% of cases. The first patient was a 35-year-old male who presented with recurring headaches, and the second patient was a 50-year-old male who reported sudden onset of dizziness and vomiting. Computed tomography scans were performed in both cases, but magnetic resonance imaging played a crucial role in the characterization of the lesions and their locations in the thalamus, third ventricle, lateral ventricles, and cerebellopontine angle area. The final diagnosis was confirmed through pathological examination and immunohistochemistry following brain tumor resection. These cases underscore the significance of magnetic resonance imaging in the early diagnosis of intracranial extranodal Rosai-Dorfman disease.

Published in Radiology Case Reports

ISSN: 1930-0433 (Online)
Publisher: Elsevier
Country of publisher: United States
LCC subjects: Medicine: Medicine (General): Medical physics. Medical radiology. Nuclear medicine
Website: http://www.journals.elsevier.com/radiology-case-reports/

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