Clinical and Applied Thrombosis/Hemostasis (Oct 2022)

Clinical Application of Thromboelastography in Acute Ischemic Stroke

  • Feng Chen BS,
  • Liren Zhang MS,
  • Xiaolin Bai BS,
  • Xiuzhe Wang PhD,
  • Zhi Geng MS

DOI
https://doi.org/10.1177/10760296221131801
Journal volume & issue
Vol. 28

Abstract

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Acute ischemic stroke (AIS), characterized by high morbidity and mortality, has imposed a considerable burden on society. Despite rapid development in the treatment of AIS, there is still a high risk of recurrence. Furthermore, there is a time delay in waiting for the results of conventional coagulation tests in candidate patients for intravenous thrombolysis therapy. Heterogeneous responses to antiplatelet, intravascular thrombolysis, and endovascular therapies also worsen the situation. Thromboelastography (TEG), as a global and portable detection method for hemostasis, facilitates clinicians in disease monitoring, treatment evaluation, and prognosis prediction in AIS. In this narrative review, we provided a comprehensive summary of the clinical application of TEG in ischemic stroke and gave insights to further studies.