Journal of Pharmacy and Bioallied Sciences (Jan 2024)

Evaluation of dissolution of pulp by sodium hypochlorite when mixed with tetrasodic etidronate and disodic ethylenediamine tetraacetate under controlled flow

  • Mukesh Kumar,
  • Siddharth Shahi,
  • Lalit Kumar Agarwal,
  • Fahiem Mohammad Mohammad El-Shamy,
  • Khushboo Gupta,
  • Nidhi Aggarwal

DOI
https://doi.org/10.4103/jpbs.jpbs_940_23
Journal volume & issue
Vol. 16, no. 5
pp. 684 – 686

Abstract

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Background: Sodium hypochlorite serves as the most efficient root canal irrigating fluid. Objectives: This study's goal was to assess the replenished NaOCl's capacity to dissolve the tissue of pulp when combined with 9% tetrasodic etidronate (Na4HEBP), 18% tetrasodic etidronate (Na4HEBP), and 17% disodic ethylenediaminetetraacetate (Na2EDTA) under continuous controlled administration. Materials and Methods: Hundred and twenty complete undamaged teeth of the anterior mandible extracted due to periodontal problems within forty-eight hours were taken as a source of the pulp tissue. Results: It was found that there was a decrease in the weight of pulp tissue in all groups except negative control. Conclusion: NaOCl's potential to dissolve tissue with chelating agents like EDTA and HEBP inside the root canal was unaffected when there was controlled administration of EDTA and HEBP.

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