Journal of Cardiovascular Development and Disease (Mar 2024)

Incremental Value of Biventricular Strain in Patients with Severe Aortic Stenosis

  • Camille Sarrazyn,
  • Xavier Galloo,
  • Maria Chiara Meucci,
  • Steele C. Butcher,
  • Kensuke Hirsawa,
  • Rinchyenkhand Myagmardorj,
  • Frank van der Kley,
  • Tine De Backer,
  • Jeroen J. Bax,
  • Nina Ajmone Marsan

DOI
https://doi.org/10.3390/jcdd11030090
Journal volume & issue
Vol. 11, no. 3
p. 90

Abstract

Read online

(1) Background: Left ventricular global longitudinal (LVGLS) and right ventricular free wall strain (RVFWS) demonstrated separate prognostic values in patients with severe aortic stenosis (AS). However, studies evaluating the combined assessment of LVGLS and RVFWS have shown contradictory results. This study explored the prognostic value of combining LVGLS and RVFWS in a large group of severe AS patients referred for transcatheter aortic valve implantation. (2) Methods: Patients were classified into three groups: preserved (LVGLS ≥ 15% AND RVFWS > 20%), single-ventricle impaired (LVGLS p p = 0.015) and biventricular-impaired strain groups (HR 1.920; 95% CI: 1.134–3.250; p = 0.015) were independently associated with all-cause mortality. These findings were confirmed with a sensitivity analysis in patients with preserved LV ejection fraction. (4) Conclusions: In patients with severe AS, biventricular strain allows better risk stratification, even if LV ejection fraction is preserved.

Keywords