Communications Biology (Aug 2021)

Ultrastructural analysis in yeast reveals a meiosis-specific actin-containing nuclear bundle

  • Tomoko Takagi,
  • Masako Osumi,
  • Akira Shinohara

DOI
https://doi.org/10.1038/s42003-021-02545-9
Journal volume & issue
Vol. 4, no. 1
pp. 1 – 11

Abstract

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Using freeze-substitution electron microscopy, Takagi et al identify nuclear actin-containing bundles within meiotic yeast cells. These bundles are absent in stages other than meiosis I and in spo11 mutants defective in homologous recombination, allowing authors to speculate that these bundles may be involved in meiotic chromosome movement or in protecting the nucleus from mechanical stress during cell division.