Frontiers in Immunology (Jun 2024)

Necroptosis in bacterial infections

  • Xing Yu,
  • Jin Yuan,
  • Linxi Shi,
  • Shuying Dai,
  • Lei Yue,
  • Min Yan

DOI
https://doi.org/10.3389/fimmu.2024.1394857
Journal volume & issue
Vol. 15

Abstract

Read online

Necroptosis, a recently discovered form of cell-programmed death that is distinct from apoptosis, has been confirmed to play a significant role in the pathogenesis of bacterial infections in various animal models. Necroptosis is advantageous to the host, but in some cases, it can be detrimental. To understand the impact of necroptosis on the pathogenesis of bacterial infections, we described the roles and molecular mechanisms of necroptosis caused by different bacterial infections in this review.

Keywords