Nature Communications (May 2020)
The UK Biobank imaging enhancement of 100,000 participants: rationale, data collection, management and future directions
- Thomas J. Littlejohns,
- Jo Holliday,
- Lorna M. Gibson,
- Steve Garratt,
- Niels Oesingmann,
- Fidel Alfaro-Almagro,
- Jimmy D. Bell,
- Chris Boultwood,
- Rory Collins,
- Megan C. Conroy,
- Nicola Crabtree,
- Nicola Doherty,
- Alejandro F. Frangi,
- Nicholas C. Harvey,
- Paul Leeson,
- Karla L. Miller,
- Stefan Neubauer,
- Steffen E. Petersen,
- Jonathan Sellors,
- Simon Sheard,
- Stephen M. Smith,
- Cathie L. M. Sudlow,
- Paul M. Matthews,
- Naomi E. Allen
Affiliations
- Thomas J. Littlejohns
- Nuffield Department of Population Health, University of Oxford
- Jo Holliday
- Nuffield Department of Population Health, University of Oxford
- Lorna M. Gibson
- Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
- Steve Garratt
- UK Biobank Coordinating Centre
- Niels Oesingmann
- UK Biobank Coordinating Centre
- Fidel Alfaro-Almagro
- Centre for Functional MRI of the Brain, Wellcome Centre for Integrative Neuroimaging, University of Oxford
- Jimmy D. Bell
- Research Centre for Optimal Health, University of Westminster
- Chris Boultwood
- UK Biobank Coordinating Centre
- Rory Collins
- Nuffield Department of Population Health, University of Oxford
- Megan C. Conroy
- Nuffield Department of Population Health, University of Oxford
- Nicola Crabtree
- Birmingham Women’s and Children’s NHS Foundation Trust
- Nicola Doherty
- UK Biobank Coordinating Centre
- Alejandro F. Frangi
- Department of Cardiovascular Sciences and Electrical Engineering, KU Leuven
- Nicholas C. Harvey
- MRC Lifecourse Epidemiology Unit, University of Southampton
- Paul Leeson
- Radcliffe Department of Medicine, University of Oxford
- Karla L. Miller
- Centre for Functional MRI of the Brain, Wellcome Centre for Integrative Neuroimaging, University of Oxford
- Stefan Neubauer
- Radcliffe Department of Medicine, University of Oxford
- Steffen E. Petersen
- William Harvey Research Institute, Queen Mary University of Medicine
- Jonathan Sellors
- Nuffield Department of Population Health, University of Oxford
- Simon Sheard
- UK Biobank Coordinating Centre
- Stephen M. Smith
- Centre for Functional MRI of the Brain, Wellcome Centre for Integrative Neuroimaging, University of Oxford
- Cathie L. M. Sudlow
- Usher Institute of Population Health Sciences and Informatics, University of Edinburgh
- Paul M. Matthews
- Department of Brain Sciences, Imperial College London and UK Dementia Research Institute
- Naomi E. Allen
- Nuffield Department of Population Health, University of Oxford
- DOI
- https://doi.org/10.1038/s41467-020-15948-9
- Journal volume & issue
-
Vol. 11,
no. 1
pp. 1 – 12
Abstract
Between 2014 and 2023, 100,000 UK Biobank participants are undergoing brain, heart and abdominal MRI, as well as DXA and carotid ultrasound scans. In this review, authors provide a detailed overview of the rationale for the collection of these imaging data, the procedures of data collection and management, and the future directions of the UK biobank imaging enhancement.
