Nature Communications (May 2016)

The complete local genotype–phenotype landscape for the alternative splicing of a human exon

  • Philippe Julien,
  • Belén Miñana,
  • Pablo Baeza-Centurion,
  • Juan Valcárcel,
  • Ben Lehner

DOI
https://doi.org/10.1038/ncomms11558
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 8

Abstract

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Genotype–phenotype landscapes are an important characteristic for understanding the evolution of traits. Here the authors construct the local landscape for the alternative splicing of FAS/CD95 exon 6, revealing the regulation of splicing and the evolution of regulatory information between species.