Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure

Michela Faggioni; Domenico G Della Rocca; Sanghamitra Mohanty; Chintan Trivedi; Ugur Canpolat; Carola Gianni; Amin Al-Ahmad; Rodney Horton; Gerald Joseph Gallinghouse; John David Burkhardt; Andrea Natale

doi:10.15420/cfr.2019.03

Cardiac Failure Review (Apr 2020)

Long-term Outcome of Pulmonary Vein Isolation Versus Amiodarone Therapy in Patients with Coexistent Persistent AF and Congestive Heart Failure

Michela Faggioni,
Domenico G Della Rocca,
Sanghamitra Mohanty,
Chintan Trivedi,
Ugur Canpolat,
Carola Gianni,
Amin Al-Ahmad,
Rodney Horton,
Gerald Joseph Gallinghouse,
John David Burkhardt,
Andrea Natale

Affiliations

Michela Faggioni: Department of Medicine, James J Peters Veterans Affairs Medical Center, New York, NY, US
Domenico G Della Rocca: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Sanghamitra Mohanty: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Chintan Trivedi: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Ugur Canpolat: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US; Department of Cardiology, Faculty of Medicine, Hacettepe University, Ankara, Turkey
Carola Gianni: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Amin Al-Ahmad: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Rodney Horton: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Gerald Joseph Gallinghouse: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
John David Burkhardt: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US
Andrea Natale: Texas Cardiac Arrhythmia Institute, St David’s Medical Center, Austin, TX, US; Interventional Electrophysiology, Scripps Clinic, La Jolla, CA, US; Department of Cardiology, MetroHealth Medical Center, School of Medicine, Case Western Reserve University, Cleveland, OH, US; Division of Cardiology, Stanford University, Stanford, CA, US; Atrial Fibrillation and Arrhythmia Center, California Pacific Medical Center, San Francisco, CA, US

DOI: https://doi.org/10.15420/cfr.2019.03
Journal volume & issue: Vol. 6

Abstract

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Although pharmacological rhythm control of AF in patients with heart failure with reduced ejection fraction (HFrEF) does not seem to provide any benefit over rate control, catheter ablation of AF has been shown to improve clinical outcomes. These results can be explained with higher success rates of catheter ablation in restoring and maintaining sinus rhythm compared with antiarrhythmic drugs. In addition, pharmacotherapy is not void of side-effects, which are thought to offset its potential antiarrhythmic benefits. Therefore, efforts should be made towards optimisation of ablation techniques for AF in patients with HFrEF.

Published in Cardiac Failure Review

ISSN: 2057-7540 (Print); 2057-7559 (Online)
Publisher: Radcliffe Medical Media
Country of publisher: United Kingdom
LCC subjects: Medicine: Internal medicine: Specialties of internal medicine: Diseases of the circulatory (Cardiovascular) system
Website: https://www.cfrjournal.com/

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