A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity

Angkana T. Huang; Bernardo Garcia-Carreras; Matt D. T. Hitchings; Bingyi Yang; Leah C. Katzelnick; Susan M. Rattigan; Brooke A. Borgert; Carlos A. Moreno; Benjamin D. Solomon; Luke Trimmer-Smith; Veronique Etienne; Isabel Rodriguez-Barraquer; Justin Lessler; Henrik Salje; Donald S. Burke; Amy Wesolowski; Derek A. T. Cummings

doi:10.1038/s41467-020-18450-4

Nature Communications (Sep 2020)

A systematic review of antibody mediated immunity to coronaviruses: kinetics, correlates of protection, and association with severity

Angkana T. Huang,
Bernardo Garcia-Carreras,
Matt D. T. Hitchings,
Bingyi Yang,
Leah C. Katzelnick,
Susan M. Rattigan,
Brooke A. Borgert,
Carlos A. Moreno,
Benjamin D. Solomon,
Luke Trimmer-Smith,
Veronique Etienne,
Isabel Rodriguez-Barraquer,
Justin Lessler,
Henrik Salje,
Donald S. Burke,
Amy Wesolowski,
Derek A. T. Cummings

Affiliations

Angkana T. Huang: Department of Biology, University of Florida
Bernardo Garcia-Carreras: Department of Biology, University of Florida
Matt D. T. Hitchings: Department of Biology, University of Florida
Bingyi Yang: Department of Biology, University of Florida
Leah C. Katzelnick: Department of Biology, University of Florida
Susan M. Rattigan: Department of Biology, University of Florida
Brooke A. Borgert: Department of Biology, University of Florida
Carlos A. Moreno: Department of Biology, University of Florida
Benjamin D. Solomon: National Human Genome Research Institute, National Institutes of Health
Luke Trimmer-Smith: Department of Biology, University of Florida
Veronique Etienne: Emerging Pathogens Institute, University of Florida
Isabel Rodriguez-Barraquer: Division of HIV, ID, and Global Medicine, University of California
Justin Lessler: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health
Henrik Salje: Department of Biology, University of Florida
Donald S. Burke: Department of Epidemiology, University of Pittsburgh
Amy Wesolowski: Department of Epidemiology, Johns Hopkins Bloomberg School of Public Health
Derek A. T. Cummings: Department of Biology, University of Florida

DOI: https://doi.org/10.1038/s41467-020-18450-4
Journal volume & issue: Vol. 11, no. 1
pp. 1 – 16

Abstract

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Antibody mediated immunity to SARS-CoV-2 will affect future transmission and disease severity. This systematic review on antibody response to coronaviruses, including SARS-CoV-2, SARS-CoV, MERS-CoV and endemic coronaviruses provides insights into kinetics, correlates of protection, and association with disease severity.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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