Nature Communications (May 2016)

Identification of proliferative progenitors associated with prominent postnatal growth of the pons

  • Robert A. Lindquist,
  • Cristina D. Guinto,
  • Jose L. Rodas-Rodriguez,
  • Luis C. Fuentealba,
  • Matthew C. Tate,
  • David H. Rowitch,
  • Arturo Alvarez-Buylla

DOI
https://doi.org/10.1038/ncomms11628
Journal volume & issue
Vol. 7, no. 1
pp. 1 – 16

Abstract

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Postnatal growth of the pons is not well characterized. Here the authors show that growth of the murine pons is fastest during postnatal day 0–4, a period preceding myelination, and is primarily driven by an expansion of the oligodendrocyte population that derive from Sox2+Olig2+progenitors.