Journal of Ginseng Research (Jan 2021)

Adaptogenic effects of Panax ginseng on modulation of immune functions

  • Zubair Ahmed Ratan,
  • Soo Hyun Youn,
  • Yi-Seong Kwak,
  • Chang-Kyun Han,
  • Mohammad Faisal Haidere,
  • Jin Kyeong Kim,
  • Hyeyoung Min,
  • You-Jung Jung,
  • Hassan Hosseinzadeh,
  • Sun Hee Hyun,
  • Jae Youl Cho

Journal volume & issue
Vol. 45, no. 1
pp. 32 – 40

Abstract

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Traditional medicinal practices have used natural products such as adaptogens to treat inflammatory, autoimmune, neurodegenerative, bacterial, and viral diseases since the early days of civilization. Panax ginseng Myer is a common herb used in East Asian countries for millennia, especially in Korea, China, and Japan. Numerous studies indicate that ginseng can modulate the immune system and thereby prevent diseases. Although the human immune system comprises many different types of cells, multiple studies suggest that each type of immune cell can be controlled or stimulated by ginseng or its derivatives. Provisional lists of ginseng's potential for use against viruses, bacteria, and other microorganisms suggest it may prove to be a valuable pharmaceutical resource, particularly if higher-quality evidence can be found. Here, we reviewed the role of ginseng as an immune-modulating agent in attempt to provide a valuable starting point for future studies on the herb and the human immune system.

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