Are Trace Elements Provided for Children on Long-Term Parenteral Nutrition Adequate to Meet Their Needs?
Hanna Romanowska,
Mikołaj Danko,
Anna Borkowska,
Katarzyna Popińska,
Marta Sibilska,
Joanna Żydak,
Joanna Wielopolska,
Klaudia Bartoszewicz,
Agnieszka Szlagatys-Sidorkiewicz,
Janusz Książyk
Affiliations
Hanna Romanowska
Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology of the Developmental Age, Pomeranian Medical University, 71-252 Szczecin, Poland
Mikołaj Danko
The Children’s Memorial Health Institute, Department of Pediatrics, Nutrition and Metabolic Diseases, 04-730 Warsaw, Poland
Anna Borkowska
Department of Pediatrics, Gastroenterology, Allergology and Nutrition, Medical University of Gdańsk, 80-803 Gdańsk, Poland
Katarzyna Popińska
The Children’s Memorial Health Institute, Department of Pediatrics, Nutrition and Metabolic Diseases, 04-730 Warsaw, Poland
Marta Sibilska
The Children’s Memorial Health Institute, Department of Pediatrics, Nutrition and Metabolic Diseases, 04-730 Warsaw, Poland
Joanna Żydak
The Children’s Memorial Health Institute, Department of Pediatrics, Nutrition and Metabolic Diseases, 04-730 Warsaw, Poland
Joanna Wielopolska
Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology of the Developmental Age, Pomeranian Medical University, 71-252 Szczecin, Poland
Klaudia Bartoszewicz
Department of Pediatrics, Endocrinology, Diabetology, Metabolic Diseases and Cardiology of the Developmental Age, Pomeranian Medical University, 71-252 Szczecin, Poland
Agnieszka Szlagatys-Sidorkiewicz
Department of Pediatrics, Gastroenterology, Allergology and Nutrition, Medical University of Gdańsk, 80-803 Gdańsk, Poland
Janusz Książyk
The Children’s Memorial Health Institute, Department of Pediatrics, Nutrition and Metabolic Diseases, 04-730 Warsaw, Poland
Background: We conducted a cross-sectional study to investigate whether children receiving long-term parenteral nutrition (LPN) are at risk of imbalances in selected trace elements. Methods: Serum levels of manganese, zinc, copper, selenium, and iodine were measured in 83 children on LPN and compared with 121 healthy controls. Children with signs of infection or elevated C-reactive protein levels were excluded. Elemental analysis was performed using inductively coupled plasma mass spectrometry (ICP-MS). Results: Manganese and copper levels were significantly lower in the study group compared with controls (p p p p p p Conclusions: Serum concentrations of manganese, copper, and selenium in the study group remained within normal ranges, even though children weighing over 15 kg received doses below those recommended by scientific guidelines. An iodine intake below 1 μg/kg/day in patients weighing over 15 kg appears insufficient. Patients on LPN required a higher zinc intake than current recommendations.
