Infectious Diseases of Poverty (Aug 2023)
Immediate and long-term outcomes after treat-all among people living with HIV in China: an interrupted time series analysis
- Xinsheng Wu,
- Guohui Wu,
- Ping Ma,
- Rugang Wang,
- Linghua Li,
- Yinghui Sun,
- Junjie Xu,
- Yuwei Li,
- Tong Zhang,
- Quanmin Li,
- Yuecheng Yang,
- Lijing Wang,
- Xiaoli Xin,
- Ying Qiao,
- Bingxue Fang,
- Zhen Lu,
- Xinyi Zhou,
- Yuanyi Chen,
- Qi Liu,
- Gengfeng Fu,
- Hongxia Wei,
- Xiaojie Huang,
- Bin Su,
- Hui Wang,
- Huachun Zou
Affiliations
- Xinsheng Wu
- Shenzhen Campus of Sun Yat-sen University
- Guohui Wu
- Institute for AIDS/STD Control and Prevention, Chongqing Center for Disease Control and Prevention
- Ping Ma
- Department of Infectious Diseases, Tianjin Second People’s Hospital
- Rugang Wang
- Dalian Public Health Clinical Center
- Linghua Li
- Infectious Disease Center, Guangzhou Eighth People’s Hospital, Guangzhou Medical University
- Yinghui Sun
- Shenzhen Campus of Sun Yat-sen University
- Junjie Xu
- Clinical Research Academy, Peking University Shenzhen Hospital, Peking University
- Yuwei Li
- Shenzhen Campus of Sun Yat-sen University
- Tong Zhang
- Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University
- Quanmin Li
- Infectious Disease Center, Guangzhou Eighth People’s Hospital, Guangzhou Medical University
- Yuecheng Yang
- Dehong Prefecture Center for Disease Control and Prevention
- Lijing Wang
- Shijiazhuang Fifth Hospital
- Xiaoli Xin
- No.6 People’s Hospital of Shenyang
- Ying Qiao
- No.2 Hospital of Hohhot
- Bingxue Fang
- Shenzhen Campus of Sun Yat-sen University
- Zhen Lu
- Shenzhen Campus of Sun Yat-sen University
- Xinyi Zhou
- Shenzhen Campus of Sun Yat-sen University
- Yuanyi Chen
- Shenzhen Campus of Sun Yat-sen University
- Qi Liu
- Shenzhen Campus of Sun Yat-sen University
- Gengfeng Fu
- Department of STD/AIDS Control and Prevention, Jiangsu Provincial Center for Disease Control and Prevention
- Hongxia Wei
- Department of Infectious Disease, The Second Hospital of Nanjing, Nanjing University of Chinese Medicine
- Xiaojie Huang
- Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University
- Bin Su
- Clinical and Research Center for Infectious Diseases, Beijing Youan Hospital, Capital Medical University
- Hui Wang
- National Clinical Research Centre for Infectious Diseases, The Third People’s Hospital of Shenzhen and The Second Affiliated Hospital of Southern, University of Science and Technology
- Huachun Zou
- School of Public Health, Fudan University
- DOI
- https://doi.org/10.1186/s40249-023-01119-7
- Journal volume & issue
-
Vol. 12,
no. 1
pp. 1 – 14
Abstract
Abstract Background In 2003, China implemented free antiretroviral therapy (ART) for people living with HIV (PLHIV), establishing an eligibility threshold of CD4 50 (+ 7.8%, IRR = 1.078, 95% CI: 1.000–1.161; P = 0.046), heterosexual transmission (+ 12.4%, IRR = 1.124, 95% CI: 1.042–1.213; P = 0.002) and Southwestern China (+ 12.9%, IRR = 1.129, 95% CI: 1.055–1.208; P < 0.001) in the first month of treat-all. Conclusions The implementation of treat-all policy in China was associated with a positive effect on HIV care and treatment outcomes. To advance the work of rapid ART, efforts should be made to streamline the testing and ART initiation process, provide comprehensive support services, and address the issue of uneven distribution of medical resources.
Keywords
