Frontiers in Molecular Neuroscience (Oct 2024)

Editorial: Protein post-translational modifications in the nervous system: from development to disease and ageing

  • Beatriz Alvarez,
  • Beatriz Alvarez,
  • Judit Symmank,
  • Geraldine Zimmer-Bensch,
  • Miguel Diaz-Hernandez,
  • Miguel Diaz-Hernandez,
  • Patricia Franzka

DOI
https://doi.org/10.3389/fnmol.2024.1501719
Journal volume & issue
Vol. 17

Abstract

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Graphical AbstractPTMs are crucial for biological processes contributing to healthy organ function. Protein post-translational modifications (PTMs), such as phosphorylation (P), acetylation (Ac), SUMOylation (SUMO), S-nitrosylation (Nitro), ubiquitination (Ub) and glycosylation (Glyco), affect a wide range of cellular and biological functions as depicted in this cartoon. Perturbations lead to severe consequences for the normal function of the brain and other organs, such as muscle. Created in BioRender. Hübner (2024) BioRender.com/j49w898.

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