Peculiarities of course of an acute cholecystitis in patients with obesity

Abstract

Objective. To study peculiarities of course of an acute cholecystitis, development of complications and mortality in patients with obesity. Materials and methods. The data, concerning 387 patients, suffering an acute cholecystitis, were analyzed retrospectively. There were following criteria of the patients’ exclusion from the investigation: chronic cholecystitis or is acute phase; age lesser than 18 yrs; incomplete spectrum of investigations performed; obturation jaundice, including those, suffering oncological disease; excessive body mass.The diagnosis was confirmed by application of ultrasonographic investigation and CT. Results. Of 387 patients, suffering an acute cholecystitis, 208 (53.7%) had obesity (the investigated group). In a control group there were 179 (46.3%) patients. The patients, suffering obesity, were younger than patients in a control group: (47.53 ± 2.04) and (54.5 ± 1.63) yrs, accordingly (p=0.01, α=0.05). In the investigation group there were in 1.2 times more women. In the patients with obesity operative intervention was longer - (91.3 ± 0.65) min, than in patients of a control group - (73.7 ± 0.75) min (p=0.001; α=0.05). Potent positive correlational link between two variables (r=0,9078) was established with the determination coefficient R2=0.8213; p=0.001. This have witnessed, that with the 95% CI the body mass index in up to 82% patients the operative intervention variety depends on. Conclusion. In the patients with obesity the operative intervention duration and the conversion rate enhances, as well as the stationary stay and the postoperative wounds infectioning rate, increasing the treatment expenses. In the patients with obesity mortality is a statistically nonsignificant.

Keywords

• an acute cholecystitis; obesity; laparoscopy; cholecystectomy