Lysine benzoylation is a histone mark regulated by SIRT2

He Huang; Di Zhang; Yi Wang; Mathew Perez-Neut; Zhen Han; Y. George Zheng; Quan Hao; Yingming Zhao

doi:10.1038/s41467-018-05567-w

Nature Communications (Aug 2018)

Lysine benzoylation is a histone mark regulated by SIRT2

He Huang,
Di Zhang,
Yi Wang,
Mathew Perez-Neut,
Zhen Han,
Y. George Zheng,
Quan Hao,
Yingming Zhao

Affiliations

He Huang: Ben May Department for Cancer Research, The University of Chicago
Di Zhang: Ben May Department for Cancer Research, The University of Chicago
Yi Wang: School of Biomedical Sciences, University of Hong Kong
Mathew Perez-Neut: Ben May Department for Cancer Research, The University of Chicago
Zhen Han: Department of Pharmaceutical and Biomedical Sciences, University of Georgia
Y. George Zheng: Department of Pharmaceutical and Biomedical Sciences, University of Georgia
Quan Hao: School of Biomedical Sciences, University of Hong Kong
Yingming Zhao: Ben May Department for Cancer Research, The University of Chicago

DOI: https://doi.org/10.1038/s41467-018-05567-w
Journal volume & issue: Vol. 9, no. 1
pp. 1 – 11

Abstract

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Histone marks regulate chromatin structure and function. Here the authors identify and characterize lysine benzoylation, a histone mark that can be modulated by sodium benzoate, a widely used chemical food preservative, associated with specific regulation of gene expression.

Published in Nature Communications

ISSN: 2041-1723 (Online)
Publisher: Nature Portfolio
Country of publisher: United Kingdom
LCC subjects: Science
Website: https://www.nature.com/ncomms/

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